University of California San Francisco

Michael D. Alvarado, MD

Michael D. Alvarado - 144x
Michael D. Alvarado, MD

Professor of Surgery
Interim Chief, Section of Breast Care Surgery
Division of Surgical Oncology
Director, Breast Surgery Oncology Fellowship

Address

550 16th Street, #6352
San Francisco, CA 94158
United States

Email: [email protected]

Biography

Dr. Michael Alvarado is a cancer surgeon who cares for patients with breast cancer and melanoma at the UCSF Helen Diller Family Comprehensive Cancer Center at Mount Zion.

In his research, Alvarado conducts trials of radiation therapy for breast cancer. He also studies blood-based and molecular markers with the goal of improving breast cancer screening.

Alvarado earned a master's degree in chemistry at the University of Arizona and a medical degree at Dartmouth College’s Geisel School of Medicine. After completing a residency at Dartmouth-Hitchcock Medical Center, he completed a surgical oncology fellowship at the H. Lee Moffitt Cancer Center and Research Institute at the University of South Florida.

Videos

Education

Institution Degree Dept or School End Date
Darmouth M.D. School of Medicine 1998

Board Certifications

  • 2005, American Board of Surgery

Clinical Expertise

Breast Reconstruction
DCIS (Ductal Carcinoma in situ)
Inflammatory Breast Cancer
Invasive Breast Cancer
LCIS (Lobular Carcinoma in situ)
Lumpectomy/Partial Mastectomy
Lymphadenectomy
Mastectomy
Melanoma
Merkel Cell Carcinoma
Recurrent Breast Cancer
Sentinel Lymph Node Biopsy
Wire Localization Surgery

Clinical Trials

  1. Post-operative Radiotherapy Omission in Selected Patients With Early Breast Cancer Trial International VErsion (PROSPECTIVE) (NCT06445738)
    Related Conditions: Breast Cancer, MRI, Neuroimaging| Start Date: | End Date:
  2. Intraoperative Radiation Therapy in Treating Patients With Breast Cancer Undergoing Breast-Conserving Surgery (NCT01570998)
    Related Conditions: Breast Cancer| Start Date: | End Date:
  3. SentiMag® Intraoperative Comparison in Breast Cancer (NCT02336737)
    Related Conditions: Breast Cancer| Start Date: | End Date:

Program Affiliations

  • UCSF Helen Diller Family Comprehensive Cancer Center
  • UCSF Melanoma Center
  • Carol Franc Buck Breast Care Center

Research Interests

Investigation of blood-based and molecular markers to improve breast cancer screening
Sentinel Lymph Node Biopsy

Publications

MOST RECENT PUBLICATIONS FROM A TOTAL OF 10
  1. Longitudinal tumor-informed ctDNA monitoring for recurrence and treatment response in melanoma.
    Sleeper O, Fortino J, Cho NW, Daud AI, Tsai KK, Lee JC, Alvarado M, Maker AV, Liu L, Kim C, Chan JW| | PubMed
  2. Logic, reason, and freethought: The case against axillary dissection after neoadjuvant therapy.
    Alvarado M| | PubMed
  3. Oncological outcomes with and without axillary lymph node dissection in patients with residual micrometastases after neoadjuvant chemotherapy (OPBC-07/microNAC): an international, retrospective cohort study.
    Montagna G, Alvarado M, Myers S, Mrdutt MM, Sun SX, Sevilimedu V, Barrio AV, van den Bruele AB, Boughey JC, Boyle MK, Crown A, Kesmodel SB, King TA, Kuerer HM, Leisha EC, Moo TA, Weiss A, Williams AD, Parmar P, Diskin B, Hlavin C, Diego EJ, Polidorio N, Abdelwahab K, Banys-Paluchowski M, Kurzeder C, Heidinger M, Goldschmidt M, Schulz A, Heil J, Karadeniz Cakmak G, Pislar N, Riis M, Prakash I, Ovalle V, Ugurlu MU, Franceschini G, Sergeevich EA, Morales J, Lee HB, Galimberti V, Ahn SG, Ryu JM, Muslumanoglu M, Cabioglu N, Yoo TR, Vrancken Peeters MJ, Ferrucci M, Morrow M, Weber WP, microNAC Study Group| | PubMed
  4. FNA biopsy of breast specimens effectively harvests cells for patient-derived organoids modeling ductal carcinoma in situ.
    Ye J, Goldhammer N, Vohra P, Warhadpande S, de Castro GC, Rodas CKM, Moasser MM, Ramalingam K, Abe SE, Alvarado M, Ewing C, Goodwin KM, Mukhtar RA, Wong JM, Esserman LJ, Balassanian R, Rosenbluth JM| | PubMed
  5. Disparities in the Surgical Management of the Axilla by Self-Identified Race in the Multicenter Neoadjuvant I-SPY2 Trial.
    Kaur M, Dimitroff K, Boughey JC, Esserman LJ, Yau C, Tchou J, Quirarte A, Lee MC, Howard-McNatt MM, Switalla K, Kuerer H, Sauder C, Postlewait LM, Arciero C, Rao R, Wallace A, Reyna C, Ahmed K, Gutnik L, Taunk N, Perlmutter J, DeMichele A, Yee D, Hylton NM, Symmans WF, Rugo HS, Shatsky RA, Isaacs C, Rudra S, Pohlmann P, Ewing C, Wong J, Alvarado M, Jaskowiak N, Prionas N, Golshan M, Piltin MA, Olopade OI, Mukhtar RA| | PubMed
  6. Limitations in the Application of Clinicopathologic Factors Alone in Predicting Radiation Benefit for Women With Low-Risk Ductal Carcinoma In Situ After Breast Conserving Surgery: The Impact of a 7-Gene Biosignature Based on 10-Year Ipsilateral Breast Rec
    Vicini F, Shah C, Mittal K, Weinmann S, Leo M, Mann GB, Warnberg F, Rabinovitch R, Czerniecki B, Meattini I, Khan AJ, Jhawar S, Gerber N, Willey SC, Borgen P, AlHilli Z, Kruse M, Dabbs D, Shivers SC, Daily A, Whitworth P, Alvarado M, Mouabbi JA, Moran M, Rugo H, O'Shaughnessy JA, Bremer T| | PubMed
  7. Single-Cell Analyses Reveal a Functionally Heterogeneous Exhausted CD8+ T-cell Subpopulation That Is Correlated with Response to Checkpoint Therapy in Melanoma.
    Mahuron KM, Shahid O, Sao P, Wu C, Haugh AM, Huppert LA, Levine LS, Lowe MM, Alvarado M, Micu M, Tsai KK, Chow M, Singer M, Schenkel JM, Sharpe AH, Rosenblum MD, Pauken KE, Daud AI| | PubMed
  8. Bilateral Mastectomy vs Lumpectomy and Breast Cancer Mortality Risk.
    O'Keefe TJ, Alvarado MD, Esserman LJ| | PubMed
  9. Balancing risks of surgical complications and positive margins for patients with invasive lobular carcinoma of the breast and elevated BMI: An institutional cohort study.
    Falade I, Switalla K, Quirarte A, Baxter M, Soroudi D, Rothschild H, Abe SE, Goodwin K, Piper M, Alvarado M, Julian BQ, Ewing C, Wong J, Rose J, Esserman L, Foster R, Mukhtar RA| | PubMed
  10. Comparing the effectiveness of lumbar medial branch radiofrequency coagulation using 18-gauge and 16-gauge cannulae.
    Landers MH, Newton F, Alvarado M, Bogduk N| | PubMed